The DrTims Aquatics Saltwater One & Only Live Nitrifying Bacteria is an effective solution to eliminating the New Tank Syndrome. This product immediately creates a biofilter to naturally remove toxic ammonia and nitrite from your water. The best results occur when you set up a new tank, after water changes, cleaning the filter, and adding new fish. This product also helps to control ammonia and nitrite levels in your water, which is safe to add at any time.